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New Anesthesia research.

The strongest recent Anesthesia papers on PubMed, ranked by study design, topic and journal, with the same summaries subscribers get.

  1. randomized trial, 61 patients

    Shared and Differential Psychological Processes Associated With Treatment Response in Mindful Self-Compassion and Cognitive-Behavioural Therapy for Chronic Pain: An Exploratory Secondary Analysis of a Randomized Controlled Trial

    Torrijos-Zarcero M, Roca P, Rocamora-González C, et al. Eur J Pain. Oct 2026.

    Findings
    In this secondary analysis of a randomized trial, MSC (n = 61) produced larger increases in pain acceptance and reductions in helplessness, with acceptance/self‑compassion and helplessness/self‑compassion pathways explaining up to 51% of change in depression, anxiety and mental quality of life.
    Bottom line
    Acceptance and reduced helplessness accounted for up to 51% of improvement in emotional outcomes for MSC compared with CBT.

    PubMed, PMID 42894379

  2. randomized trial, 356 patients

    Prophylactic Low-Dose Esketamine for Prevention of Intraoperative Penile Erection During Ureteroscopic Surgery Under General Anesthesia: A Randomized, Double-Blind, Placebo-Controlled Trial

    Zhang Z, Yin G, He W, et al. Drug Des Devel Ther. Jan 2026.

    Findings
    In 356 patients, rESULTS: The incidence of IPE was 6.2% (11/178) with esketamine versus 21.9% (39/178) with saline (RR 0.282, 95% CI 0.149-0.533; ARR 15.7%; NNT 6.4; P < 0.001).
    Bottom line
    Prophylactic esketamine cut IPE incidence to 6.2% (vs 21.9% saline) and lowered rescue‑treatment need to 4.5% (vs 21.3%).

    PubMed, PMID 42928869

  3. randomized trial, 196 patients

    Effect of a Subanesthetic Dose of Esketamine on Postoperative Sleep Disturbance After Oocyte Retrieval Under Intravenous Anesthesia: A Randomized Controlled Trial

    Ma Q, Li H, Wang X, et al. Drug Des Devel Ther. Jan 2026.

    Findings
    In a double‑blind, placebo‑controlled trial, 196 women undergoing oocyte retrieval under intravenous anesthesia were randomized to receive a subanesthetic dose of esketamine or placebo, and postoperative sleep disturbance was assessed.
    Bottom line
    The study evaluated the effect of esketamine on postoperative sleep in a cohort of 196 participants.

    PubMed, PMID 42894628

  4. randomized trial, 193 patients

    Impact of remote management using patient-reported outcomes on pain and anxiety after breast biopsy: the BIO-PSY randomized controlled trial

    Guerdoux E, Coutant L, Al Herk A, et al. Support Care Cancer. Oct 2026.

    Findings
    Among 193 women undergoing breast biopsy, anxiety was significantly lower in the PRO‑monitoring arms versus standard care at day 4 (p < 0.001) and remained lower at day 10 for the phone‑based arm (adjusted p = 0.008).
    Bottom line
    Remote PRO monitoring reduced post‑biopsy anxiety (p < 0.001 at day 4).

    PubMed, PMID 42911430

  5. randomized trial, 72 patients

    A non-inferiority randomized controlled trial comparing nebulized fentanyl and intravenous morphine for acute pain management in the emergency department

    Preungprasob P, Rojsaengroeng R, Hengrasmee C, et al. BMC Emerg Med. Jul 2026.

    Findings
    In a randomized trial, pain reduction was measured at 15 min. The nebulized fentanyl group reported a mean score of 5.56 with a standard deviation of 1.66, while the intravenous morphine group reported 5.67 ± 1.85. The difference was statistically significant (p < 0.001).
    Bottom line
    Both treatments lowered pain similarly at 15 min (5.56 ± 1.66 vs 5.67 ± 1.85; p < 0.001).

    PubMed, PMID 42907741

Summaries are written by AI from PubMed abstracts, for keeping up with the literature. Check the source before it changes care. Editorial policy · Medical disclaimer

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