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New Endocrine Surgery research.

The strongest recent Endocrine Surgery papers on PubMed, ranked by study design, topic and journal, with the same summaries subscribers get.

  1. meta-analysis, 479 patients

    Preoperative parathyroid imaging in CKD-related secondary hyperparathyroidism: a systematic review and diagnostic test accuracy network meta-analysis

    Vetrano D, Barbuto S, Mistretta A, et al. Clin Kidney J. Oct 2026.

    Findings
    Across ten studies (479 patients), ¹⁸F‑FCH PET/CT achieved 89.6% sensitivity, markedly higher than US (64.2%) and MIBI SPECT/CT (68.8%).
    Bottom line
    ¹⁸F‑FCH PET/CT provides the highest estimated sensitivity (89.6%) for pre‑operative parathyroid localization in CKD‑related SHPT.

    PubMed, PMID 42924101

  2. phase ii trial, 24 patients

    Sequential Therapy with Anlotinib and Radioiodine for Distant Metastatic Differentiated Thyroid Cancer: A Phase II Clinical Trial

    Song H, Shen C, Fan Y, et al. Oncologist. Oct 2026.

    Findings
    In a Phase II study, 24 patients were enrolled. Ten (42%) with RAI‑avid lesions received sequential therapy for a median of 4.5 cycles. The objective response rate was 60% (all partial responses) and disease control was achieved in 100% of participants. Grade 3 anlotinib‑related adverse events occurred in 30% of patients.
    Bottom line
    The regimen produced a 60% response and 100% disease control, but grade 3 toxicity affected 30% of patients.

    PubMed, PMID 42911655

  3. meta-analysis, 8 studies

    Intraoperative facial nerve monitoring on operative duration in parotidectomy: a systematic review and meta-analysis

    Chen JL, Lin IC, Shen EY, et al. Head Face Med. Jul 2026.

    Findings
    The systematic review included 8 studies comprising 1677 patients.
    Bottom line
    Findings are drawn from 8 studies and 1677 patients.

    PubMed, PMID 42907851

  4. phase ii trial, 40 patients

    Cobimetinib + Vemurafenib in Patients With BRAF V600E-Mutant Papillary Thyroid and Biliary Tract Cancers: Results From the TAPUR Study

    Diamond-Rossi SA, Rothe M, Garrett-Mayer E, et al. JCO Precis Oncol. Oct 2026.

    Findings
    In patients with BRAF V600E-mutant thyroid cancer, the disease control rate was 94% and the objective response rate was 63%. In biliary tract cancer, disease control and response rates were 67% and 53%, respectively.
    Bottom line
    Cobimetinib plus vemurafenib shows significant antitumor activity in BRAF V600E-mutant thyroid and biliary tract cancers.

    PubMed, PMID 42886887

  5. prospective cohort, 56 patients

    Impact of Triple Assessment on Surgical Decision-making in Thyroid Nodule Management

    Rajgor M, Bagwan MB. Ann Afr Med. Oct 2026.

    Findings
    In 56 patients undergoing thyroid nodule surgery, triple assessment using clinical examination, ultrasonography, and FNAC achieved 100% sensitivity, 87.50% specificity, and an overall diagnostic accuracy of 97.86%.
    Bottom line
    Combining clinical examination, ultrasonography, and FNAC provides high diagnostic accuracy and reduces false-negative results in thyroid nodule evaluation.

    PubMed, PMID 42893837

  6. registry cohort, 15,251 patients

    Variability in the Risk of Malignancy in Bethesda IV Thyroid Nodules: Results from the EUROCRINE Surgical Registry

    Wiśniewski P, Śledziński M, Barczyński M, et al. Cancers (Basel). Oct 2026.

    Findings
    In a cohort of 15,251 patients, adjusted center-level ROM-BIV ranged from 5.5% to 65.5%. The fixed model component yielded an AUC-ROC of 0.647 with a 95% CI of 0.637-0.656.
    Bottom line
    Risk of malignancy for Bethesda IV nodules shows marked variability across centers, and the predictive model offers limited-to-moderate discrimination.

    PubMed, PMID 42882882

  7. observational study, 1322

    Preventive strategies for postoperative hypocalcemia and hungry bone syndrome following parathyroidectomy: a systematic review and pairwise meta-analysis

    Hu K, Zhang M, Ye M. Gland Surg. Sep 2026.

    Findings
    Fifteen studies with 1,322 participants evaluated various preventive strategies. Preventive intravenous calcium was associated with less severe postoperative hypocalcemia in 2 non-randomized studies (396 participants; adjusted OR 0.12).
    Bottom line
    Preventive intravenous calcium may reduce short-term hypocalcemia in secondary hyperparathyroidism, but serious confounding limits definitive conclusions.

    PubMed, PMID 42866445

  8. registry cohort

    Prevalence and Outcomes of Thyroid Nodules with Atypia of Undetermined Significance (AUS) Cytology in a Tertiary Government Hospital: A Ten-year Review (2013 to 2022)

    Valle AMF, Argamosa DTR. Acta Med Philipp. Jan 2026.

    Findings
    RESULTS: The overall frequency of Bethesda Category III (AUS/FLUS) cases in PGH and PRL was 4.27%, which is within the recommended threshold of less than 7% specified by the Bethesda System for Reporting Thyroid Cytopathology.
    Bottom line
    The low prevalence (4.27%) and infrequent repeat biopsies (15.38% and 18.64%) suggest adherence to recommended Bethesda limits.

    PubMed, PMID 42923555

Summaries are written by AI from PubMed abstracts, for keeping up with the literature. Check the source before it changes care. Editorial policy · Medical disclaimer

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