BriefMD

Specialties / Endocrinology

New Endocrinology research.

The strongest recent Endocrinology papers on PubMed, ranked by study design, topic and journal, with the same summaries subscribers get.

  1. randomized trial

    Gut virome remodeling after fecal microbiota transplantation is associated with virus-bacteria co-variation and metabolic response in obesity and type 2 diabetes

    Jiang H, Peng Y, Lam B, et al. Gut Microbes. Dec 2026.

    Findings
    Random forest classification gave 84.8% accuracy for post‑FMT virome changes and 81.4% for bacteriome changes in distinguishing LDL responders. Donor viral contig engraftment occurred in 64.7% (11/17) of recipients with FMT alone and 58.8% (10/17) with FMT plus lifestyle intervention, compared with 5.6% (1/18) in the sham plus lifestyle group.
    Bottom line
    Virome remodeling after FMT shows comparable predictive power to bacteriome shifts and markedly higher donor viral engraftment than sham treatment.

    PubMed, PMID 42912803

  2. randomized trial, 84 patients

    Dual benefit of esketamine-based opioid-free anesthesia on postoperative pain and mental health outcomes in patients undergoing bariatric surgery: a randomized controlled trial

    Huang C, Guan Z, Wang S, et al. Transl Psychiatry. Jul 2026.

    Findings
    A total of 84 patients were randomized (42 per arm) and 74 (88.1%) completed 3‑month follow‑up; esketamine‑based OFA yielded significantly lower pain intensity (P < 0.01) and better mental health outcomes.
    Bottom line
    Esketamine‑based opioid‑free anesthesia improves postoperative analgesia and mental health without raising adverse events in bariatric surgery patients.

    PubMed, PMID 42893989

  3. randomized trial, 72 patients

    Semaglutide modulates explore/exploit decision-making in major depressive disorder: A randomized clinical trial

    Zhang Z, Chen N, Wang D, et al. Psychol Med. Oct 2026.

    Findings
    In a randomized clinical trial, 72 participants with major depressive disorder were assigned to receive either oral semaglutide (n = 35) or placebo (n = 37).
    Bottom line
    The study compared outcomes between 35 participants on semaglutide and 37 on placebo.

    PubMed, PMID 42904347

  4. randomized trial, 33 patients

    Association of an almond-based low-carbohydrate diet with continuous glucose monitoring metrics in patients with type 2 diabetes mellitus: a randomized controlled trial

    Li X, Xu Y, Wang X, et al. Nutr Diabetes. Jul 2026.

    Findings
    In 33 patients, the almond‑based low‑carbohydrate diet increased nighttime TIR to 98.51% compared with 91.67% on a low‑fat diet and raised TITR to 94.14% versus 77.58%, while reducing nighttime TAR to 0.00% and glucose variability (SD 15.57 ± 6.21 mg/dL vs 23.62 ± 9.12 mg/dL).
    Bottom line
    The almond diet markedly improves nocturnal glycemic control, achieving higher TIR and TITR and lower TAR and variability.

    PubMed, PMID 42894020

Summaries are written by AI from PubMed abstracts, for keeping up with the literature. Check the source before it changes care. Editorial policy · Medical disclaimer

Get Endocrinology research every morning.

Free. Choose your Endocrinology topics after you subscribe.