Specialties / Family Medicine
New Family Medicine research.
The strongest recent Family Medicine papers on PubMed, ranked by study design, topic and journal, with the same summaries subscribers get.
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prospective cohort, 44 patients
Diaphragmatic Rapid Shallow Breathing Index Versus Diaphragmatic Thickness Fraction for Predicting Weaning Success in Mechanically Ventilated Patients
Baloda R, Chhikara M, Shiva S, et al. Cureus. Sep 2026.
- Findings
- In 44 mechanically ventilated adults, diaphragmatic rapid shallow breathing index (D-RSBI ≥ 1.2) predicted successful weaning with AUC 0.99 (95% CI 0.97-1.00, sensitivity 94.44%, specificity 100%), outperforming diaphragmatic thickness fraction (AUC 0.65, DeLong p = 0.004).
- Bottom line
- D-RSBI superiorly predicts mechanical ventilation weaning success compared to diaphragmatic thickness fraction.
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prospective cohort, 180 patients
Prediction of Acute Kidney Injury with Venous Excess Ultrasound (VExUS) Scoring Versus Renal Resistive Index (RRI) in Patients Undergoing On-Pump Coronary Artery Bypass Grafting: A Prospective Observational Study
Prusty S, Kamal M, Mohammed S, et al. Ann Card Anaesth. Oct 2026.
- Findings
- In 180 adults undergoing on-pump CABG, postoperative renal resistive index (RRI ≥ 0.68) predicted acute kidney injury within 48 hours with AUROC 0.854 (sensitivity 75%, specificity 86%), outperforming VExUS scoring (AUROC 0.623).
- Bottom line
- Postoperative renal resistive index superiorly predicts acute kidney injury after on-pump CABG compared to VExUS.
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prospective cohort, 100 patients
Three-Point Bedside Congestion Score (IJV Collapsibility + IVC Collapsibility + Central Venous Pressure) in Elective Mitral Valve Surgery: A Prospective Observational Study
Sharma M, Rajesh VSP, RamKiran KS, et al. Ann Card Anaesth. Oct 2026.
- Findings
- In 100 patients undergoing elective mitral valve surgery, a high preoperative bedside congestion score (3 vs 0-2) was associated with increased AKI (40% vs 20%) and mortality (10% vs 2%). The combined score plus TAPSE model yielded AUCs of 0.77 for AKI and 0.782 for mortality.
- Bottom line
- Preoperative bedside congestion scoring combined with TAPSE stratifies risk after mitral valve surgery.
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randomized trial
Gut virome remodeling after fecal microbiota transplantation is associated with virus-bacteria co-variation and metabolic response in obesity and type 2 diabetes
Jiang H, Peng Y, Lam B, et al. Gut Microbes. Dec 2026.
- Findings
- Random forest classification gave 84.8% accuracy for post‑FMT virome changes and 81.4% for bacteriome changes in distinguishing LDL responders. Donor viral contig engraftment occurred in 64.7% (11/17) of recipients with FMT alone and 58.8% (10/17) with FMT plus lifestyle intervention, compared with 5.6% (1/18) in the sham plus lifestyle group.
- Bottom line
- Virome remodeling after FMT shows comparable predictive power to bacteriome shifts and markedly higher donor viral engraftment than sham treatment.
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randomized trial, 595 patients
Telemedicine Consultation for Pediatric Trauma in Community ED Visits and Parent Experience of Care: A Stepped-Wedge Cluster-Randomized Clinical Trial
Marcin JP, Rosenthal JL, Tancredi DJ, et al. JAMA Netw Open. Oct 2026.
- Findings
- Telemedicine consultation did not significantly alter overall parent experience of care (AMD, 0.041; P = .10) or parent distress (AMD, -0.031; P = .82). However, discharge and transfer experience ratings were higher with telemedicine (AMD, 0.104; P = .01).
- Bottom line
- Routine pediatric trauma telemedicine did not significantly reduce parent distress or transfer odds (aOR 0.59; P = .43), though transition care ratings improved.
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randomized trial, 61 patients
Rapid and robust effects of high-dose intermittent Transcranial Brain Stimulation (iTBS) on depression and suicidal ideation in adolescents with acute major depression: a 10-day randomised, controlled, single-blind trial
Yang Y, Ye Q, Peng Z, et al. BMC Psychiatry. Jul 2026.
- Findings
- Ten daily sessions of high-dose iTBS significantly lowered HAMD-24 depression scores (p = 0.008) and suicidal ideation scores (p = 0.011) compared to sham. These improvements persisted through Week 6.
- Bottom line
- High-dose iTBS rapidly improves depressive symptoms and suicidal ideation in adolescents, though poorer family functioning links to diminished benefit (p < 0.05).
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randomized trial, 94 patients
Risperidone for children with attention-deficit/hyperactivity disorder and severe behavioral dysregulation: a randomized placebo-controlled assessor-blinded trial
Abbasi E, Abdi A, Eskandari R. BMC Psychiatry. Jul 2026.
- Findings
- Adjunctive risperidone reduced 48-week ADHD-RS-IV scores to 15.63 ± 1.82 versus 26.47 ± 2.92 with placebo (p < 0.001). Risperidone also achieved a higher clinical response rate (70.8% vs. 21.7%; p < 0.001).
- Bottom line
- In children with treatment-refractory behavioral dysregulation and ADHD, risperidone significantly improved clinical response (70.8% vs. 21.7%, p < 0.001) alongside higher parent-rated improvements.
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randomized trial, 10 patients
An intravaginal ring for HIV pre-exposure prophylaxis: assessment of safety and pharmacokinetics in a randomized, placebo-controlled clinical trial
Vincent KL, Moss JA, Marzinke MA, et al. Front Cell Infect Microbiol. Jan 2026.
- Findings
- Median vaginal tissue concentrations of TFV diphosphate reached 0.651×103 fmol mg-1 and FTC triphosphate reached 0.180×103 fmol mg-1. High median CVF concentrations of TFV (38.9 ng mg-1) and FTC (239 ng mg-1) were also attained.
- Bottom line
- The TDF-FTC intravaginal ring achieved targeted tissue drug levels without evidence of a statistically significant difference in related adverse-event counts between products.
Summaries are written by AI from PubMed abstracts, for keeping up with the literature. Check the source before it changes care. Editorial policy · Medical disclaimer
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