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New Neurosurgery research.

The strongest recent Neurosurgery papers on PubMed, ranked by study design, topic and journal, with the same summaries subscribers get.

  1. meta-analysis, 10 studies

    STN-SNr co-stimulation in Parkinson's disease: a systematic review and meta-analysis of motor and freezing-of-gait outcomes

    Kong L, Li P, Bi Y, et al. Neurol Sci. Oct 2026.

    Findings
    Adding SNr to STN stimulation showed no difference in UPDRS-III across 73 participants (MD - 0.10, 95% CI - 1.01 to 0.81). It also provided no additional freezing-of-gait benefit across 86 participants (Hedges' g - 0.23, 95% CI - 1.04 to 0.59).
    Bottom line
    Current evidence does not support routine STN-SNr co-stimulation for motor or gait symptoms in Parkinson's disease.

    PubMed, PMID 42909654

  2. randomized trial, 60 patients

    Comparison of dexmedetomidine and droperidol-fentanyl for asleep-awake-asleep techniques in awake craniotomy anesthesia: a randomized controlled study

    Yang X, Qu D, Ren Y, et al. BMC Anesthesiol. Jul 2026.

    Findings
    In the trial, the dexmedetomidine group showed lower mean arterial pressure at time points T4‑T7 and lower heart rate at T1‑T4 and T7. A total of 61 patients were randomized and 60 were included in the final analysis.
    Bottom line
    Dexmedetomidine produced reductions in MAP and HR at the specified time points compared with droperidol‑fentanyl.

    PubMed, PMID 42897460

  3. systematic review, 31 studies

    MRI-Based Machine Learning to Differentiate True Progression from Pseudoprogression in Glioblastoma: An Updated Systematic Review and Meta-Analysis

    Zhang X, Guo X, Wang Y, et al. Neuro Oncol. Oct 2026.

    Findings
    In external test cohorts, MRI-based machine learning distinguished true progression from pseudoprogression with a pooled sensitivity of 0.78, specificity of 0.75, and summary AUC of 0.81. Internal validation cohorts showed a non-significantly higher AUC of 0.91.
    Bottom line
    MRI machine learning shows moderate-to-good accuracy, but small cohorts and risk of bias limit immediate clinical application.

    PubMed, PMID 42898007

  4. systematic review, 17 studies

    Comparison of non-invasive neuromodulation for motor function rehabilitation in incomplete spinal cord injury: a systematic review and network meta-analysis

    Han Y, Han J, Wang H, et al. BMC Neurol. Jul 2026.

    Findings
    Across 17 RCTs, iTBS improved lower-limb strength (SMD = 0.87) and gait speed (SMD = 0.52). 20 Hz-rTMS reduced spasticity (MD = - 0.41), while 10 Hz-rTMS yielded the greatest gain in functional independence (SMD = 1.03).
    Bottom line
    Non-invasive neuromodulation techniques such as iTBS and rTMS improve specific motor and functional domains after incomplete spinal cord injury.

    PubMed, PMID 42902225

Summaries are written by AI from PubMed abstracts, for keeping up with the literature. Check the source before it changes care. Editorial policy · Medical disclaimer

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