BriefMD

Specialties / Otolaryngology

New Otolaryngology research.

The strongest recent Otolaryngology papers on PubMed, ranked by study design, topic and journal, with the same summaries subscribers get.

  1. randomized trial, 25 patients

    Effects of resistance training on subjective sleep quality, excessive daytime sleepiness, and quality of life in patients with obstructive sleep apnea: a secondary analysis from a randomized controlled trial

    de Almeida JRV, da Silva Ferreira DK, de Arantes Lima VD, et al. Sleep Breath. Oct 2026.

    Findings
    In the trial, the resistance training group showed a change in sleep latency of -1.0 ± 0.3 versus 0.2 ± 0.2 in controls (p = 0.018). The overall PSQI score changed by -3.2 ± 0.6 compared with 0.2 ± 0.8 in controls (p = 0.004). Emotional aspects shifted by 29.6 ± 14.8 versus -17.9 ± 10.0 (p = 0.008).
    Bottom line
    Resistance training produced statistically significant improvements in sleep latency, global sleep quality, and emotional health metrics for patients with obstructive sleep apnea.

    PubMed, PMID 42900248

  2. randomized trial, 46 patients

    Protective effect of N-acetylcysteine on oxaliplatin-induced peripheral neuropathy in colorectal cancer: a randomized controlled trial

    Hegazy ZK, Tawfik SK, Elmashad NM. Cancer Chemother Pharmacol. Oct 2026.

    Findings
    In the trial, neurotensin fell significantly in the NAC arm versus control (P < 0.001). IL‑6 also dropped significantly (P < 0.001). FACT/GOG‑NTX‑12 and NCI‑CTCAE scores were lower in the NAC group at the end of the first two cycles and at study end (P < 0.05).
    Bottom line
    N‑acetylcysteine markedly reduced neurotensin, IL‑6 and neuropathy severity (P < 0.001, P < 0.001, P < 0.05).

    PubMed, PMID 42909655

  3. randomized trial, 72 patients

    A Bioequivalence Study of Two Formulations of Enzalutamide Soft Capsules in Healthy Chinese Male Subjects

    Wang J, Gu K, Zhang M, et al. Clin Pharmacol Drug Dev. Oct 2026.

    Findings
    In 72 healthy Chinese men, the test enzalutamide soft capsule demonstrated 90% confidence intervals for Cmax and AUC0‑72 h within the 80‑125% bioequivalence range, and no serious adverse events occurred.
    Bottom line
    The generic enzalutamide capsule is bioequivalent to the reference product (90% CI 80‑125%) and shows a comparable safety profile.

    PubMed, PMID 42910839

  4. meta-analysis, 9,322 patients

    Use of autofluorescence and/or indocyanine green in thyroid surgery: recommendations by the European Society of Endocrine Surgeons (ESES)

    Van Den Heede K, Triponez F, Agcaoglu O, et al. Br J Surg. Oct 2026.

    Findings
    The review screened 335 abstracts and identified 34 studies comprising 9322 patients, including 11 randomized controlled trials. These data underpin the new ESES guidance on using NIRAF with or without ICG during thyroidectomy.
    Bottom line
    Clinicians can base their use of NIRAF/ICG on evidence from 34 studies (9322 patients, 11 RCTs).

    PubMed, PMID 42929023

Summaries are written by AI from PubMed abstracts, for keeping up with the literature. Check the source before it changes care. Editorial policy · Medical disclaimer

Get Otolaryngology research every morning.

Free. Choose your Otolaryngology topics after you subscribe.