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New Preventive Medicine research.

The strongest recent Preventive Medicine papers on PubMed, ranked by study design, topic and journal, with the same summaries subscribers get.

  1. randomized trial, 20,250 patients

    Fecal Immunochemical Test Outreach for Colorectal Cancer Screening in Community Health Centers: A Randomized Clinical Trial

    Martinez ME, Roesch S, Largaespada V, et al. JAMA Netw Open. Oct 2026.

    Findings
    At year 2, screening was 37.8% in intervention clinics versus 27.0% in usual care clinics, a difference of 10.8 percentage points. At year 3, screening was 39.4% vs 36.5%, a non‑significant 2.9‑point gap.
    Bottom line
    FIT outreach increased 2‑year screening by 10.8 percentage points (37.8% vs 27.0%).

    PubMed, PMID 42905707

  2. randomized trial, 84 patients

    Dual benefit of esketamine-based opioid-free anesthesia on postoperative pain and mental health outcomes in patients undergoing bariatric surgery: a randomized controlled trial

    Huang C, Guan Z, Wang S, et al. Transl Psychiatry. Jul 2026.

    Findings
    A total of 84 patients were randomized (42 per arm) and 74 (88.1%) completed 3‑month follow‑up; esketamine‑based OFA yielded significantly lower pain intensity (P < 0.01) and better mental health outcomes.
    Bottom line
    Esketamine‑based opioid‑free anesthesia improves postoperative analgesia and mental health without raising adverse events in bariatric surgery patients.

    PubMed, PMID 42893989

  3. randomized trial, 386 patients

    Effectiveness of Exercise Snacks in Mitigating Adolescent Problematic Smartphone Use: A Four-Wave Cluster Randomized Controlled Trial

    Li L, Peng B, Liu J, et al. Scand J Med Sci Sports. Nov 2026.

    Findings
    At month four, school-based exercise snacks produced a model-adjusted reduction in daily screen time of -52.22 min/day (95% CI, -67.21 to -37.23) and lowered smartphone addiction severity by -6.55 SAS-SV points (95% CI, -7.38 to -5.71) compared with control.
    Bottom line
    Short vigorous exercise snacks during school breaks significantly decrease adolescent screen time and smartphone addiction severity.

    PubMed, PMID 42925061

  4. randomized trial, 100 patients

    Clinical similarity, economic divergence: cost-effectiveness and population health implications of dietary, pharmacological, and exercise interventions in older adults with type 2 diabetes: a secondary analysis of a randomized controlled trial

    Gonen LD, Buch A, Eldor R, et al. BMC Geriatr. Jul 2026.

    Findings
    In a secondary analysis of an RCT with n = 100 participants aged 65+, the 10‑week follow‑up found that both dietary and exercise interventions were economically dominant, delivering lower costs and higher QALYs.
    Bottom line
    Among 100 older adults, a 10‑week diet or exercise program reduced costs while improving health outcomes.

    PubMed, PMID 42902215

  5. randomized trial, 23 patients

    Feasibility and safety of an exercise-based prehabilitation intervention before cancer surgery: a pilot randomised controlled trial

    Hennessy DT, Shee AW, Rawstorn JC, et al. Support Care Cancer. Oct 2026.

    Findings
    Among 23 randomized patients awaiting cancer surgery, exercise prehabilitation showed attendance of 91.3% and adherence of 82.6%. Five adverse events occurred in the prehabilitation arm, all grade 1.
    Bottom line
    Preoperative exercise prehabilitation is feasible with 91.3% attendance and 82.6% adherence, though clinical efficacy requires larger trials.

    PubMed, PMID 42905213

Summaries are written by AI from PubMed abstracts, for keeping up with the literature. Check the source before it changes care. Editorial policy · Medical disclaimer

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