Specialties / Sleep Medicine
New Sleep Medicine research.
The strongest recent Sleep Medicine papers on PubMed, ranked by study design, topic and journal, with the same summaries subscribers get.
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randomized trial, 72 patients
Cerebellar Continuous Theta Burst Stimulation for Insomnia Disorder: A Randomized Sham-Controlled Trial
Liu XY, Dong D, Song CG, et al. CNS Neurosci Ther. Oct 2026.
- Findings
- In a randomized sham‑controlled trial, 72 patients (51 women; mean age 44.3 ± 11.6 years) received cerebellar continuous theta burst stimulation. A significantly higher proportion of active‑treatment participants achieved a ≥ 3‑point PSQI improvement compared with sham (75.0% vs. 33.3%; adjusted OR 6.06; 95% CI 2.17‑18.50; p < 0.001). Only right amygdala‑right orbitofrontal connectivity showed a significant group‑by‑time interaction (FDR‑adjusted p = 0.038).
- Bottom line
- Active cerebellar cTBS markedly increased clinically meaningful insomnia improvement (75.0% vs. 33.3%) with robust odds (6.06) and altered amygdala‑orbitofrontal connectivity (p = 0.038).
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randomized trial, 120 patients
Indirect moxibustion therapy improves insomnia and associated symptoms in patients with schizophrenia
Cai J, Wu M, Zhang J. Trials. Jul 2026.
- Findings
- Adjunctive indirect moxibustion significantly improved PSQI sleep quality scores compared to sham at week 8 (10.65 ± 1.54 vs. 12.77 ± 2.05). Quality of life differences were also significant (P < 0.001).
- Bottom line
- Indirect moxibustion provides clinically meaningful sleep and quality-of-life benefits as an adjunctive non-pharmacologic option in schizophrenia.
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randomized trial, 25 patients
Effects of resistance training on subjective sleep quality, excessive daytime sleepiness, and quality of life in patients with obstructive sleep apnea: a secondary analysis from a randomized controlled trial
de Almeida JRV, da Silva Ferreira DK, de Arantes Lima VD, et al. Sleep Breath. Oct 2026.
- Findings
- In the trial, the resistance training group showed a change in sleep latency of -1.0 ± 0.3 versus 0.2 ± 0.2 in controls (p = 0.018). The overall PSQI score changed by -3.2 ± 0.6 compared with 0.2 ± 0.8 in controls (p = 0.004). Emotional aspects shifted by 29.6 ± 14.8 versus -17.9 ± 10.0 (p = 0.008).
- Bottom line
- Resistance training produced statistically significant improvements in sleep latency, global sleep quality, and emotional health metrics for patients with obstructive sleep apnea.
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randomized trial, 36 patients
Effects of local vibration therapy and gabapentin on restless legs syndrome symptoms: a randomized controlled trial
Raissi G, Forogh B, Ansari H, et al. BMC Res Notes. Jul 2026.
- Findings
- In a randomized controlled trial, 36 participants were enrolled, with 18 assigned to local vibration therapy and 18 to gabapentin. The mean age was 45 years (SD = 10.6) in the vibration group and 49.1 years (SD = 8.3) in the gabapentin group.
- Bottom line
- Both interventions were tested in equal groups of 18 participants, showing comparable age distributions (45 ± 10.6 vs 49.1 ± 8.3 years).
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randomized trial, 196 patients
Effect of a Subanesthetic Dose of Esketamine on Postoperative Sleep Disturbance After Oocyte Retrieval Under Intravenous Anesthesia: A Randomized Controlled Trial
Ma Q, Li H, Wang X, et al. Drug Des Devel Ther. Jan 2026.
- Findings
- In a double‑blind, placebo‑controlled trial, 196 women undergoing oocyte retrieval under intravenous anesthesia were randomized to receive a subanesthetic dose of esketamine or placebo, and postoperative sleep disturbance was assessed.
- Bottom line
- The study evaluated the effect of esketamine on postoperative sleep in a cohort of 196 participants.
Summaries are written by AI from PubMed abstracts, for keeping up with the literature. Check the source before it changes care. Editorial policy · Medical disclaimer
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